refractory medical definition

Refractory celiac disease (RCD) is a complex autoimmune disorder much like the more common celiac disease but, unlike celiac disease, it is resistant or unresponsive to at least 12 months of treatment with a strict gluten-free diet. This means that the affected person continues to have seizures even when taking anti-seziure medications. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more. A number of different terms may be used to describe this type of epilepsy, including uncontrolled, intractable, refractory, or drug resistant.Refractory … Showing or characterized by obstinate resistance to authority or control: refractory children; refractory behavior. Our paper aims to summarize the current medical literature on the conceptual and methodologic issues involved in the definition, assessment, and staging of TRD. (1) To date, no randomized clinical trials examining the effects of HBO 2 therapy on not responsive or difficult to manage. Definition and synonyms of refractory from the online English dictionary from Macmillan Education.. See additional information . P. Kwan and M.J. Brodie, Early identification of refractory … Refractory bricks in a torpedo car used for hauling molten iron. Refractory: Not yielding, or not yielding readily, to treatment. The Unbiased Biomarkers for the Prediction of … Refractory. Particularly important are the potential benefits in the areas of research, treatment, and medical cost reimbursement. Generally, migraines that are not relieved by acute migraine therapies or prevented by preventive treatments are called refractory migraines, although medical experts have not yet reached a consensus on a precise definition. 2016 Dec;42(12):1948-1957. doi: 10.1007/s00134-016-4574-2. An International Working Group (IWG) defined refractory ITP as disease that does not respond to or relapses after splenectomy and that requires treatment to reduce the risk of clinically significant bleeding. adj. Read medical definition of Refractory. Then, intractable, the one works best is highlighted in yellow – difficult to alleviate, remedy or cure: intractable pain. 1. Learn more. For example: If the diagnosis is corrected and seizures can be brought under control with a different treatment, then they would not be considered refractory. NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. The term refractory shock is applied when, in spite of apparently adequate therapy, the shock … FPnotebook.com is a rapid access, point-of-care medical reference for primary care and emergency clinicians. refractory depression (TRD), a condition that causes significant social and economic burdens. Patients with severe refractory asthma pose a major healthcare problem. 1. Definition of refractory adjective in Oxford Advanced Learner's Dictionary. There, clinicians have several different approaches they can try to curb the progression of the disease and … refractory definition: 1. not affected by a treatment, change, or process: 2. difficult to control; unwilling to obey…. ... or advice of a legal, medical, or any other professional. Examples of Refractory in a sentence. Refractory lining synonyms, Refractory lining pronunciation, Refractory lining translation, English dictionary definition of Refractory lining. MedicineNet does not provide medical advice, diagnosis or treatment. home / medterms medical dictionary a-z list / anemia, refractory definition In some cases, refractory migraine is used synonymously with chronic migraine, or referred to as intractable migraine. Properly diagnosed seizures do not respond to the best medical treatment. (See "Medical management of gastroesophageal reflux disease in adults".) EXCITABILITY & REFRACTORY PERIODS osms.it/excitability-refractory-periods Refractory period Time in which myocardial cell cannot be depolarized Absolute refractory period: no stimulus, no matter its size, can depolarize cell Phases 0, 1; part of phase 2 Effective refractory period: large stimulus can generate action … Refractory and Intractable – The refractory is, when you’re reading the definitions, the one that is the best from medical terms is – resistant to treatment: a refractory case of acne. Over the last decade it has become increasingly clear that, for the development of new targeted therapies, there is an urgent need for further characterisation and classification of these patients. It is 2007-12-07ot;difficult” symptoms, since many symptoms considered refractory are at times successfully managed by specialized hospice and palliative care programs (Broeckaert 2002).The malignant tumors most often associated with refractory … Intensive Care Med. Author information: (1)Dartmouth Hitchcock Medical Center-Neurology, Lebanon, NH, USA. His session was dedicated to recognizing the various pathophysiologic processes that may contribute to refractory chronic rhinosinusitis (CRS) and to describing the available medical and treatment options. In view of these issues, the term refractory ascites has often generated confusion in the past and made it difficult to compare the results of clinical studies performed by … Other articles where Refractory shock is discussed: cardiovascular disease: Refractory and irreversible shock: The terms refractory shock and irreversible shock are widely used by physicians and other medical workers to refer to types of shock that present particularly difficult problems. Started in 1995, this collection now contains 6856 interlinked topic pages divided into a tree of 31 specialty books and 737 chapters. To make his life easier, the store owner decided to fire the refractory workers who were difficult to manage. Some experts define a patient as having refractory seizures if treatment fails to achieve seizure freedom for 12 months or more, for whatever reason (1). Refractory definition, hard or impossible to manage; stubbornly disobedient: a refractory child. The generally accepted definition of refractory seizures was proposed by Berg: failure of two or more drugs and occurrence of one or more seizures per month over 18 months (2). Refractory acute myeloid leukemia (AML) is a very challenging complication in the management of AML. The causes, symptoms, and treatment of refractory epilepsy, which develops when your seizures aren't brought under control by medicine. Definition and diagnostic criteria of refractory ascites. 2 The American Society of Hematology ITP Guidelines endorsed this definition as a means of identifying the most severely … The most common definition includes five elements: two of the fifth period (niobium … 🔊 Most teenagers go through a refractory phase where they don’t want to listen to authority figures. Refractory metals are a class of metals that are extraordinarily resistant to heat and wear.The expression is mostly used in the context of materials science, metallurgy and engineering.The definition of which elements belong to this group differs. A refractory symptom may be subjective and, at times, nonspecific. Definition of Refractory. Chronic refractory cough (CRC) is defined as a cough that persists despite guideline based treatment. Refractory Depression – Treatment, Definition, Severe March 24th, 2012 admin Types of Depression 0 comments Depression in itself is a complicated disorder, but there may be further complications that can make treating the … Approximately one-fourth of the patients who fail medical therapy and then undergo ESS will be diagnosed with refractory … The clinical manifestations, diagnosis, and initial medical management of GERD are discussed in detail separately. We use cookies to enhance your experience on our website, including to provide targeted advertising and track usage. The relative refractory period refers to that period of time after the initiation of one action potential when it is … Since true refractory celiac disease is so rare, patients who've been diagnosed with either form will most likely be referred to a celiac center with experience treating refractory forms of the disease. Refractory septic shock in children: a European Society of Paediatric and Neonatal Intensive Care definition. The term high temperatures is somewhat indefinite but usually means above about 1830°F (1000°C), or temperatures at which, because of melting or oxidation, the common metals cannot be used. They are … Refractory osteomyelitis is defined as a chronic osteomyelitis that persists or recurs after appropriate interventions have been performed or where acute osteomyelitis has not responded to accepted management techniques. Refractories are inorganic, nonmetallic, porous, and heterogeneous. TERMINOLOGY — The definition of refractory gastroesophageal reflux disease (GERD) is controversial . Title: refractory - definition of refractory in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclop Author: tighe See more. Learn more. Not all uncontrolled seizures are considered refractory or drug resistant. Several terms have been used to describe this condition, … Method: We reviewed the recently published medical literatureto … Epub 2016 Oct 5. The absolute refractory period refers to that period of time after the initiation of one action potential when it is impossible to initiate another action potential no matter what the stimulus intensity used. Refractory epilepsy: a type of epilepsy that cannot be controlled by medications. This definition was created based on the information from the REACH1 and REACH2 trials along with retrospective studies showing that 10–14 days was the median time to initial response following the start of ruxolitinib treatment in patients with steroid-refractory aGvHD. This is the British English definition of refractory.View American English definition of refractory.. Change your default dictionary to American English. One of a number of ceramic materials for use in high-temperature structures or equipment. 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